The maximum blood concentration (Cmax) of Ofirmev is higher than with oral or rectal administration; however, it is important to note that the Cmax with Ofirmev (29 mcg/mL) remains far below the 150 mcg/ mL concentration considered potentially hepatotoxic.
...
Ofirmev exposes the liver to approximately 50% less acetaminophen compared with equivalent doses of oral acetaminophen. This lack of first-pass metabolism and resultant decrease in liver exposure likely play a role in the low incidence of hepatic damage reported with Ofirmev thus far.
So it's safer than taking pills, at least from what I'm reading.
The funny thing about wanting warrant-compatible encryption is that warrants don't have any technical features by themselves to decode anything.
Me: "Hey, I need to get my sunglasses out of your car."
Friend: "Oh, sure, go ahead." <stands there>
Me: "Ummm ... I need your keys."
The warrant is the permission, but what gets you into the car are the keys. What they're really asking for is all the keys but obscuring it by talking about warrants. And once they have them, it'll be really easy to give themselves permission to use them any time they want.
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Re: how harmful is IV acetaminophen?
I am not a Dr, but I Google: https://www.pharmacytimes.com/publications/health-system-edition/2012/jan-2012/-iv-acetaminophen-ofirmev-
... So it's safer than taking pills, at least from what I'm reading."Warrant-compatible encryption"
The funny thing about wanting warrant-compatible encryption is that warrants don't have any technical features by themselves to decode anything.
Me: "Hey, I need to get my sunglasses out of your car."
Friend: "Oh, sure, go ahead." <stands there>
Me: "Ummm ... I need your keys."
The warrant is the permission, but what gets you into the car are the keys. What they're really asking for is all the keys but obscuring it by talking about warrants. And once they have them, it'll be really easy to give themselves permission to use them any time they want.