DailyDirt: This Is Your Brain On Caffeine. Any Questions?

from the urls-we-dig-up dept

Making the perfect cup of coffee is an experiment that's been studied for decades -- if not for hundreds of years since coffee was first brewed in the 1300s. It's not an exact science yet, but studies on coffee drinking seem to point to it being mostly beneficial. Here are just a few interesting links for coffee lovers out there. If you'd like to read more awesome and interesting stuff, check out this unrelated (but not entirely random!) Techdirt post via StumbleUpon.
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Filed Under: caffeine, coffee, decaf, decaffeinated coffee, drinks, drugs, food, health, medicine, pregnant


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  1. identicon
    Anonymous Coward, 31 Aug 2013 @ 6:59am

    Re: caffeine factoid...

    Ummm.... That's not right at all about the caffeine LD50.

    So LD50 in mice for Caffeine is 192 mg/Kg(when ingested orally) in rats.(Just wait for it.) In humans LD50 is considered 150-200 mg/Kg depending on sensitivities and what not. So we take an average human(180 lbs, convert to Kilograms 180/2.2 = 81.81repeating. Take that number and multily by the mean of the LD50(I say is 175 mg/Kg) = 14.318repeating Grams is the LD50.

    For cocaine it is roughly guessimated(All sites never broke past 1.5G so I decided to use this number) to be 1.2-1.5 Grams for a human. So in other words cocaine is a significant figure more lethal than cocaine.

    So instead we'll use a different method. We can assume that a ratio of LD50s when compared to in Rats will produce a ratio that should represent the approximate ratio in humans.

    Therefore the LD50 of caffeine for rats is 260 mg/Kg(Injected into cavern) and for cocaine it is 92mg/Kg(Injected into cavern.) This produces an approximate ratio of cocaine being 3 times more lethal than caffeine, which is supported above.

    http://www.erowid.org/psychoactives/health/psychoactives_ld50s.shtml
    http://emedicine.med scape.com/article/813959-overview
    http://en.wikipedia.org/wiki/Caffeine

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