I'm an italian reader of TD.
Berlusconi is an anomaly in all possible senses. Main examples could be him having factual control on 2 of the 3 branches of the state - legislative and executive - and attacking the judicial power every other day throughout the media. Or as well, controlling the media in the first place, from the papers to the TV, with a massive influence on the state televisions, besides his own channels which are basically as powerful.
On AGCOMs independency - AGCOMs members are elected among the members of the parliament, with the president being nominated by the prime minister, so you cant really consider it an independent agency. On a side note, some of its members, as far as I can remember, belong to Berlunsconi's party. Im not very well informed on this but apparently its representation mirrors the political forces in the parliament.
But anyhoo, what I guess is most important, the regulation doesnt address YouTube alone, but all user generated content broadcasting services that meet the criteria (a turnover of at least €100.000, and a weekly broadcasting schedule of at least 24 hours).
I dont think the regulation will sort much effect eventually, I think this may conflict ECs directives which Im currently too lazy to look up.