Reader Comments (rss)

(Flattened / Threaded)

1.  

   What about kids with 17,000 IQs?

   

   dorpus, Jun 28th, 2004 @ 6:30am

   
   

   Should we talk about the three major causes of cancer: oncogenes, oncoviruses, failure of tumor repression genes? Oncogenes typically fall into three categories of proteins involved in cell signaling: growth factors, tyrosine kinases, and transcription factors. For example, the proto-oncogene ras is a signal transducer, normally inactivated by extracellular signals. The smart child will learn about the chemical cycle starting with growth factor, receptor tyrosine-kinase, membrane-associated G-protein, serine/threonine kinases, transcription factors, and finally the CDK/cyclin/E2F which trigger passage through the restriction point. We would also cover chronic myelogenous leukimia, in which the leukemic cells have a reciprocal translocation between chromosomes 9 and 22. In addition, we will go over the p53 tumor supressor gene, coding for a transcription factor, its failure to trigger apoptosis. The final examination at the end of the game will also cover the difference between intercalating agents such as acrydine orange and alkylative agents such as nitroguanidine. For extra credit, the gifted child will draw diagrams showing the difference between a vertical cut and horizontal cut in the Holliday model, and how this affects heterozygotic crossover supression.
   
   
   
   

   [ reply to this | link to this | view in thread ]

2.  

   Oh wait

   

   dorpus, Jun 28th, 2004 @ 9:19am

   
   

   ...did the kid die from cancer already? Then let's talk about selection pressures, artificial selection, and realized heritability. What is the conditional probability that the parents will die from cancer, given that their kid already died?
   

   [ reply to this | link to this | view in thread ]

3.  

   Re: Oh wait

   

   Anonymous Coward, Jun 28th, 2004 @ 9:22am

   
   

   
   sombody pull the plug on the dorpus game already please

   [ reply to this | link to this | view in thread ]

4.  

   Re: Oh wait

   

   Anonymous Coward, Jun 28th, 2004 @ 10:59am

   
   

   What a prick.

   [ reply to this | link to this | view in thread ]

5.  

   Re: What about kids with 17,000 IQs?

   

   grant, Oct 14th, 2004 @ 5:57am

   
   

   is the game
   good-eduacational
   

   [ reply to this | link to this | view in thread ]

6.  

   Bens Game

   

   Robyn Gaynard, May 23rd, 2005 @ 3:44pm

   
   

   My son was diagnosed with ALL late last summer. I just stumbled across the article about Ben's game to explain leukemia to kids. I'm sure my Ethan would love to play but I can't seem to download it, do you think you can help me find it?

   [ reply to this | link to this | view in thread ]

Add Your Comment